Recent Advances in Ultrasound Assisted Synthesis of 2,4,5-Trisubstituted Imidazoles: A Comparative Study of Effective Catalytic Systems

The imidazole moiety finds itself in a host of compounds having profound biological and medicinal properties. This has led to the quest develop cost effective, desirably greener synthetic route access this azole. In review, ultrasonic irradiation assisted syntheses trisubstitued derivatives have been discussed which make use different environment friendly efficient catalytic systems. They found give excellent yield product high purity with shorter reaction time proved be viable alternative traditional methods.